Tirzepatide in Houston.Physician-Supervised.
Tirzepatide is a once-weekly injectable medication. At Clinic 45, it is considered only after an individual medical evaluation, and always paired with nutrition, body composition analysis, and follow-up care.
The difference between losing weight and losing muscle
Weight-loss medications can affect appetite, digestion, hydration, nutrition intake, and muscle retention. A supervised program helps you understand dosing, side effects, food choices, warning signs, and what to do when progress slows.
See How We Track Progress
More than an online prescription
Unlike online apps, we don't just ship medication and leave you alone. We provide in-person body composition tracking to help ensure you are losing fat, not muscle, and offer face-to-face support when side effects occur.
We won't prescribe something just to make a sale. Your provider reviews your full health history to decide whether a GLP-1 or another medication is clinically appropriate for you.

Read the comparison as text
Why patients choose Clinic 45 for GLP-1 care: a physician-led program, over 20 years of experience, and thousands of patients served. Here is how Clinic 45 compares with a typical medication-first program on five factors.
Primary supervision
Clinic 45
- Double board-certified MD
- 20+ years of experience
- Direct, ongoing clinical care
- Comprehensive physician oversight
Typical medication-first program
- Variable oversight
- Often health coaches or NPs
- Typically less direct MD care
- May be run by non-health administrators
Clinical diagnostics
Clinic 45
- Comprehensive in-house labs for metabolic, hormonal, and liver health
- Body composition analysis
- EKG when clinically indicated
- Looks for underlying root causes
Typical medication-first program
- Often limited diagnostics
- Often self-reported weight / BMI
- Typically basic vital checks only
- May use optional mail-in kits
Treatment tools & options
Clinic 45
- Integrated medical toolbox
- FDA-approved prescription options and targeted wellness injections to support your weight loss journey
- In-house aesthetics, including skin tightening, Botox, and radiofrequency contouring
Typical medication-first program
- Often limited treatment options
- Often one-size-fits-all protocols
- Typically basic supplements or meal plans
- Limited or no in-house procedures
Care delivery model
Clinic 45
- Flexible hybrid model
- In-person clinic visits
- Virtual telehealth follow-ups
- Personalized medical coaching
Typical medication-first program
- Often online-only or occasional in-person
- Typically limited follow-up
- Often generalized, one-way support
Pricing & focus
Clinic 45
- Transparent cash pricing
- Pay-as-you-go visits; medication always quoted separately
- Itemized, predictable costs
- Whole-health focus: weight, metabolic health, and prevention
Typical medication-first program
- Often bundled or recurring fees
- Frequent upsells and add-ons
- Typically narrow weight-loss focus
Medication is prescribed only when medically appropriate. Individual treatment plans and results vary. Comparison reflects general differences in care models; services vary by provider.
We use advanced body composition analysis to track lean mass every step of the way.
Medication FAQs
How is tirzepatide different from semaglutide?
Semaglutide acts on the GLP-1 pathway. Tirzepatide acts on both the GIP and GLP-1 pathways. Your provider decides which medication, if either, is appropriate for you.
How often is tirzepatide taken?
Tirzepatide is injected once a week. Always follow the dose and schedule set by your provider and the pharmacy label.
Are medications guaranteed?
No. Medication is only prescribed when a licensed provider determines it is clinically appropriate.
Are compounded medications FDA-approved?
No. Compounded medications are not FDA-approved, and the FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
Can medication cause side effects?
Yes. Side effects can occur. Your provider will discuss risks, warning signs, dosing, and follow-up needs based on your health history.
I was already prescribed an injection. Where do I learn to use it safely?
See our patient-education page, How to Inject Your Prescribed Medication, and always follow the exact instructions from your provider and pharmacy label.
Let's find what actually fits your health
Request a visit and review your history, goals, and options with a provider who treats medication as one part of a complete program.




