• beautiful face

    Aesthetic Services

    If it makes you feel beautiful, do it!

    Book An Appointment
  • weight loss

    Weight Loss

    Make it a lifestyle, not a duty!

    We don’t diet, we live it!

    Book An Appointment
  • Internal Medicine

    Internal Medicine

    Changing lives with caring hearts. 

    Book An Appointment
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Clinic 45 is an independent medical spa and practice that is owned and supervised by Joseph E. Sleiman M.D. We focus on the areas of weight management, liposuction, aesthetics, and internal medicine to ensure you are not only confident in your appearance, but healthy as well. If you are looking for non-invasive belly fat solutions, effective weight loss pills, or scheduling a thorough liver assessment, we welcome you to contact our weight loss and aesthetic center in Houston, TX today. We look forward to helping you achieve your optimal health goal!

What Our Clients Say


Jenycee Gilder
5 stars

“They are awesome and give you a lot of information to help you get the weight down!”


- Jenycee G. 

Bulah Acosta
5 stars

“I'm a former patient of Clinic 45 but now an employee. I recently had the Lipo360/Fat Transfer done & I am completely satisfied with my results.”


- Bulah A. 

Lauren Barnes Askew
5 stars

“Great place. I have lost 5 lbs.”


- Lauren B. 

Kimberly Thompson
5 stars

“The clinic was excellent, the hospitality was good also I will be back thank you.”


- Kimberly T. 

We Strive To Provide Excellent Care For Our Patients


At Clinic 45, we are passionate about promoting disease prevention and helping to promote a healthy lifestyle for the entire family. In addition to providing our clients with a high level of quality care, we believe in being efficient and cost-effective, so we can provide our clients with service options that won’t break the bank.


As a local medical weight loss practice, Clinic 45 is proud to provide a wide range of weight loss and aesthetic services to those throughout Houston, TX.

Contact Our Team Today To Learn More!


Our team believes in providing high-quality service options for our clients that meet their specific needs to ensure they look and feel their best. We do our best to continually maintain the highest levels of professionalism, integrity, honesty, and fairness with our clients.


Whether you need diet help, you're seeking an effective weight loss procedure or are interested in utilizing one of our state-of-the-art body contouring procedures to help you gain more confidence, our team has got you covered. Give us a call today for more information regarding our service options or to schedule an appointment! 

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